GRM2 anticorps
Aperçu rapide pour GRM2 anticorps (ABIN636930)
Antigène
Voir toutes GRM2 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Purification
- Affinity chromatography purified
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Immunogène
- GRM2 antibody was raised in rabbit using a synthetic peptide conjugated to KLH as the immunogen.
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Indications d'application
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IHC-P: 4 µg/mL
Optimal conditions should be determined by the investigator. -
Restrictions
- For Research Use only
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Concentration
- Lot specific
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Buffer
- Purified by Immunoaffinity Chromatography and supplied in PBS with 0.1 % NaN3.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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Conseil sur la manipulation
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Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use. -
Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store at 4 °C for short term storage. Aliquot and store at -70 °C for long term storage.
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- GRM2 (Glutamate Receptor, Metabotropic 2 (GRM2))
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Autre désignation
- GRM2
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Sujet
- L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. The receptors in group II, including mGluRs 2 and 3, and group III, including mGluRs 4, 6, 7, and 8, (with some exceptions) prevent the formation of cyclic adenosine monophosphate, or cAMP, by activating a G protein that inhibits the enzyme adenylyl cyclase, which forms cAMP from ATP.
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Pathways
- cAMP Metabolic Process, Dicarboxylic Acid Transport
Antigène
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